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Timothy Field Allen



THE study of the positive effects of drugs upon the healthy human organism is now universally acknowledged to be the duty of every student of medicine. To supply a complete and accurate record of these effects (pathological anatomy excepted), is the aim of this work. These symptoms are recorded as facts, which, while the interpretation of their physiological action is as sure to change as physiology is to advance, will ever remain the same, and be re-read and re-interpreted with increasing clearness and satisfaction.


-The sources from which this compilation has been made are three.

First. Experiments made upon healthy individuals for the purpose of noting the affects of the drug.

Second. Effects observed after poisonous doses (accidentally or maliciously administered).

Third. Symptoms (cautiously admitted) observed in the sick after the administration of the drug.

To these must be added a VERY FEW symptoms which have never been observed as affects of drug-action, but which have been so repeatedly verified clinically, that they clearly indicate the remedy; these are designated by a small cipher (°) after the symptom.

Dr Richard Hughes

A large amount of literature has been searched that the work might be complete and reliable. Original sources have been obtained and transcribed or translated. The authorities quoted by Hahnemann (whose original publications he was in many instances, unable to obtain), have been referred to by DR. HUGHES, of England, the circumstances under which the effects were noticed, furnished us, and, when necessary, corrections made. The following simple will serve to illustrate the value and accuracy of Dr. Hughes's work:


BONETUS. Statement of occasional effects of A.

CAMERARIUS. Effects of overdosing in adults.

EPH. NAT. CUR. Effects of overdosing in an adult.

DIOSCORIDES. Only mentions beneficial effects of its external application to ulcers of the eyes.

GARDANE. Not obtainable.

GMELIN. General statement (from authors) of effects of A.

GÖTZE. Effects of A, in a patient with syphilitic ulceration.

HILDANUS. Same case as that given in full by Camerarius in Symptom 16.

HOFFMAN. Statement of ill effects of antimonial emetics.

JAMES. Not obtainable.

JOUBERT. Not obtainable.

KUNCKEL v. LOWENSTEIN. Effects of continued use.

LINDESTOLPE. General statement of the noxious effects of A. (one only of the eight symptoms referred to him appears).

LOTICHIUS. Case of overdosing in an adult.

MATTHIOLUS. (No reference given), not in his Comm. in Dioscorid.

MORGENSTERN. General statement (from authors).

NICOLAI. Not traceable.

PLINIUS. As A. was not used internally in his time, this must be as with Dioscorides.

REINDEL. Not obtainable.

SAUNDERS. General statement from observation.

SCHULZ. Not obtainable.

STAHL. Not obtainable.

WEPFER. Several cases of poisoning in man and animals.


Symptom 15. Note, "The case related in S. 16."

Symptom 16. Render last clause, "So obtuse was her sensibility that when, from the acrimony of the evacuations and her position on the back, a large and foul ulcer formed over the sacrum and coccyx, she complained of no pain from it."

Symptom 17. Note, "Not found."

Symptom 28. Note, "Not found."

Symptom 56. Note, "Not found."

Symptom 68. Bracket, note, "Preceding S. 73."

Symptom 73. Bracket, note, "After violent vomiting, left ear soon recovered, but right remained permanently deaf; reporter ascribes it to rupture of membrana tympani."

Symptom 112. Note, "Same case as S. 421."

Symptom 113. Note, "Not mentioned by James in his treatise on the Fever Powder."

Symptom 184. Note;" Hernia ventriculi after violent vomiting," and bracket.

Symptom 206. Note, "Not found."

Symptom 221. Add, "But rarely."

Symptom 224. Note, "In a dog."

Symptom 270. Render "Suffocative catarrh." Note, "Coming on fifteen days after amputation of foot (S. 381, 388), and ending in death." Bracket.


    "Dr. Allen has wished me to state the nature of my contribution to his opus magnum.
    "It has regard solely to the pathogenesies of Hahnemann. These are derived from two sources: the first, observations made by himself and his disciples; the second, cases of poisoning and overdosing recorded in medical literature. The two elements are present in the several pathogenesies in varying proportions, as may be seen from the lists given in the Monthly Homœopathic Review, for November, 1873, and the British Journal of Homœopathy for October, 1813.
    "There are thus, in Hahnemann contributions to the Materia Medica, a large number of quotations. Now, in editing any work so characterized, you will add greatly to its value if the quotations are verified by reference to the originals. Errors will creep in, and they are much more likely to occur to the citer, full of his other thoughts, than to a corrector, whose one purpose is to see that no mistake is allowed to stand. Hahnemann's quotations, like those of any other author, need verification, and experience has amply proved the usefulness of the task.
    "But there is something more. It has often been lamented that Hahnemann has given us so little information as to the circumstances under which his symptoms were observed. In the case of himself and his fellow-provers, we must await for this, till (if ever they are) their day-books are published. But as regards the observations he has cited from authors, the information we desire is (in the main) accessible to us. It only needs a search in the great libraries which aim at including all literature to find the journals, transactions, and treatises, extant in Hahnemann's day, and from which he quoted. The result is illumination. A flood of light is cast upon the separate symptoms he has furnished: we learn their subjects, the dose and preparation of the drug, the order pursued by the phenomena, and their termination. Many misconceptions which we are liable to form of them, standing alone, are removed; and the whole series becomes intelligible and available for practice.
    "Yet once again. The investigations of this kind which have been hitherto carried out, have disclosed a strange laxity on Hahnemann's part, as regards the materials he has used. Symptoms of the most questionable kind, condemned by his own canons, and such as no one now would admit into a pathogenesis or use in practice, find frequent place in the Materia Medica Pura and the Chronic Diseases. This is the unanimous judgment of all, of Rothe, Langhienz, Frank, Shipman, Reil, Sorge, Wurmb, Watzke, who have examined any part of the subject. It has been suggested in explanation, that Hahnemann left this part of his work to others, and must not be blamed for their errors; and further, that he gave these symptoms as corroborative only. But, however this may be, there they stand; undistinguished in most collections (as in Jahr and Hempel), from those which surround them, undistinguished always among themselves. They need imperatively the fullest investigation, that their real character may be exposed, and they be either dropped or stigmatized as dubious.
    "The facts thus stated had for some time been before my mind, when I undertook to arrange Belladonna for the Hahnemann Materia Medica. It was my duty to consult the originals of the 1440 symptoms, cited by Hahnemann, in his pathogenesis of this drug; and the results I arrived at (as detailed in the British Journal of Homœopathy for 1873) both quickened my sense of the need of such examinations, and showed me their feasibility for the English student. In the Monthly Homœopathic Review for November, 1873, I stated the matter at length, illustrating it by the instance of Aconite; and urged the carrying out of the investigation for all Hahnemann's medicines. No response came, and no public body took up the undertaking. My attention was then drawn to Dr. Allen's projected Encyclopedia, and it seemed to me a grievous thing that Hahnemann's pathogenesies should once more go forth to the world with their citations unverified, unillumined, unrevised. I wrote to Dr. Allen, offering to do this work for him. He closed with me at once, and liberally provided the necessary means, and I have been engaged in the investigation ever since.
    "Its results may hereafter appear in some separate and more detailed form. At present, they are incorporated into the Materia Medica as presented in these pages. In the heading, instead of a bare list of names of authors from whom Hahnemann has quoted, there is affixed to each a brief statement of the nature of his observations, sufficient to show generally the value of the symptoms derived from this source. Next, to each symptom that requires it a note is appended, throwing light upon its causation and connections. Last, all doubtful symptoms are bracketed squarely, to distinguish them from those which Hahnemann himself has bracketed, with like intent.[These symptoms will be readily distinguished by references to the authorities and to footnotes. In succeeding volumes, two kinds of brackets will be used as here suggested.] The reason for such stigma is either stated in a note, or is obvious from the account given in the heading of the nature of the author's observations. I could myself have wished, in many instances, to expunge rather than to bracket; but, in reverence for the master, Dr. Allen desires to omit nothing which he has given us, and it is left to the judgment of the reader to estimate all according to the information supplied. My notes occupy a separate division of the page, to keep them distinct from those which Hahnemann has appended to his symptoms.
    "In this Encyclopedia of Materia Medica, accordingly, the student may feel confidence that no cited symptom of Hahnemann's (save those of authors whose works I have been unable to consult) stands unverified, and that none is without the fullest light which can be cast upon its, nature and probable value."

Dr Constantine Hering

    The existence of typographical and other errors in the original text of some provings, has been brought to the notice of the editor, by DR. C. HERING, of Philadelphia. The value of these notes will be recognized by the following samples.
    Hahnemann, Chronische Krankheiten Vierto Theil, Zweite Auflage. Natrum muriat., page 382, symptom 785, "Bei kalten Becken instead of Backen." Pathogenetic Cyclopedia, part 1, by Dudgeon, 1850, page 261-4, "Cold pelvis instead of cheeks." Same Cyclopedia has, page 25-26, nine symptoms of anxiety under the head of Natr. mur.; one is not to be found in Hahnemann ("on awaking," etc.); and nine with anxiety, not to be found in Cyclopedia.
    Chronische Krankheiten Vierte Theile. Nitrum, page 475, symptom 252, instead of "Nervengegend" read Nierengegend! copied by Trinks in his Handbuch; also by Jahr and some translators.
    Sabadilla, Archiv 4, 3, page 122-156; full of errors. Stapf Beiträge, 1836, every one repeated; have gone in all the Repertories. The worst are, page 126, instead of "Wein-trinken read Warm-trinken," etc.
    AUTHORITIES are given at the beginning of each proving, and each symptom is followed by a small number referring to this list of authorities, so that any symptom may be readily traced, and reliance placed upon it according to its authority, the dose which produced it, or the time when it occurred, the time (when noted by the provers) being given in brackets after the symptom.
    TRANSLATIONS have been made with special care to preserve the accurate meaning of the original. When existing translations have been found accurate, their phraseology has been retained, in order to make as little change as possible in existing Repertories or habitual use of symptoms.
    For several years the editor has kept, added to, and elaborated a small manuscript vocabulary, which includes the most obscure terms used in describing symptoms, the translation of which has been adopted after numerous comparisons and conferences with German scholars. Much aid has been obtained from a table of terms published in the Vierteljahrschrift, especially in the matter of provincialisms. A few extracts will illustrate this part of the work.

ABGESCHLAGENHEIT. Mental dejection; physical prostration or weariness. (Compare Mattigkeit.)

ANGEGRIFFENHEIT. Indisposed; sick. (Compare Abspannung.)

DAEMISCH (see Eingenommen). Confused. (Compare Beneblung, Benommenheit, Befangenheit, and Wüstheit)

FROST. Chill. (More severe than Kälte, coldness; a more subjective or internal sensation.)

MATT. A sensation of weakness; weariness (tired, like Müde), but not such real loss of Strength as Schwach.

SCHLUND. The whole internal throat; Schlund-kopf, pharynx.

By such means the editor has endeavored to make the translations as accurate and uniform as possible, and hopes that very few errors will exist in this part of the work. The translations from the French have mostly been made by DR. G. L. FREEMAN. a good French scholar and conscientious translator.

ARRANGEMENT. -The drugs have been arranged alphabetically, which arrangement has been strictly followed, separating even Atropine and Belladonna. The only scientific or satisfactory grouping of drugs possible must be in accordance with their generic effects on the human body. Many of our drugs are too imperfectly known, and, indeed, our bodies themselves are too imperfectly known, to render such a classification possible at this time. Theoretical grouping of drugs must be left to text-books, or treatises on the Materia Medica; it is out of place in a work of this character.

SYMPTOMS are arranged in accordance with the anatomical plan. Sub-grouping has been made in accordance with the following general principles in any part:

First. General symptoms not localized definitely.

Second. Localized symptoms.

Attention has been paid to objective and subjective symptoms, and when possible the appearance of a part (objective) is first given, and afterward sensations (subjective). Symptoms denoting increased action or activity are given first; those denoting depression and loss of action or function follow.

The following scheme has been prepared and followed as strictly as possible: Scheme.

Dr Adolph Lippe

    VERIFICATIONS. -For the purpose of making the work practically useful (the great aim in view), those symptoms which have been repeatedly cured by the drug are distinguished by stars, with italics, or full-faced type; the latter class is most important. Symptoms in italics, without stars, have been repeatedly observed by provers, but not yet verified on the sick. Most generous and efficient help in this portion of the work has been rendered by two of our most distinguished therapeutists, DR. CARROLL DUNHAM and DR. AD. LIPPE. Dr. Dunham has looked over nearly all the manuscript when ready for the press, and put in his stars and italics; in Argentum nitricum, for example, he starred symptoms 6, 31, 58, 61, 67, 73, 76, 82, 89, 104, 139, 141, 148, 275, 278, 333; 335, 403, 432, 435, 438, 439, 440, 446, 447, 499, 500, 504, 511, 536, 553. Dr. Lippe has taken the trouble to send the editor the numbers of the symptoms in his Text-book which he has verified; has also made additional observations. The other verifications have been inserted by the editor, after consulting nearly the whole of the homœopathic literature. Doubtless numerous symptoms now undistinguished deserve stars. The editor will be duly thankful for any suggestions in the matter.

Dr Carroll Dunham

    It is obviously beyond the power of any one man to do, in a limited time, all the clerical and other labor which this work has required. DR. GEORGE L. FREEMAN has been constantly employed upon it, for nearly two years preceding the issue of the first volume; he has translated all, or nearly all, the French provings, has visited libraries for the purpose of copying provings and poison cases, has arranged the symptoms in accordance with the scheme, and has made up the Conditions. My partner, DR. ST. CLAIR SMITH, has furnished numerous verifications for the work, and has very efficiently assisted its progress through the press. To both these gentlemen are due our most grateful acknowledgments. To DR. H. M. SMITH we are especially indebted, for the use of his most valuable English library, complete in its files of early and recent Homœopathic literature.
    The work is now offered to the profession with the hope that, by its accuracy and completeness, it will advance the healing art, and be the means of more effectually relieving suffering.


No. 3 EAST THIRTY-THIRD ST., NEW YORK, November 1st, 1874.